Name: International Conference on Wound Care, Tissue Repair and Regenerative Medicine
Start: 2019-02-25
End: 2019-02-27
Location: Prague

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About Conference

EuroSciCon proudly announces the conference on “International Conference on Wound Care, Tissue Repair and Regenerative Medicine” during February 25-26, 2019 Prague, Czech Republic, with the theme, “Revolutionizing the Future Prospects for Health Care Research in Humans”. This Conference is one of the most important and awaited events of the year. The conference aims to bring the participants from all over the world to share their innovative ideas and views in the field of wound management and tissue engineering. EuroSciCon through its Open Access Initiative is committed to making genuine and reliable contributions to the scientific community and the primary purpose of open access movement is to disseminate scientific information to a global audience to improve knowledge sharing among practitioners and research scholars from various disciplines.

Scope and Importance

Wound care and tissue engineering is striving to focus on understanding the advancement in bioengineering and health care practitioning, developing new technologies about these fields and discovering the potential use of these mechanizations.

Who Can Attend?

The Conference welcomes all the Eminent Leaders, leading world Doctors, registered Nurses, health care professionals, Professors, Research fellows, leading universities, students, directors of association and societies, industries, etc. It is a forum to explore issues of mutual concern as well as exchange knowledge, share evidence, ideas, and generate solutions.

Why to Attend?

Wound Care 2019 will cover wide range of topics and presents the newest developments and research advancements without financial or legal constraints. People come to know about the topical issues on the important recent developments in tissue engineering, regenerative medicine and health care. This conference is aimed to expand its coverage where expert talks, young researchers presentations will be placed in every session of the meeting will be inspired and keep up your enthusiasm. We feel our expert Organizing Committee is our major asset, however your presence over the venue will add one more feather.

Why Prague, Czech Republic?

Prague is the capital and most astronomically immense city in the Czech Republic, the 14th most immensely colossal city in the European Amalgamation and additionally the historical capital of Bohemia. Situated in the north-west of the country on the Vltava river, the city is home to about 1.4 million people, while its more immensely colossal urban zone is estimated to have a population of 2.2 million. The city has a temperate climate, with warm summers and algid winters. Prague has been a political, cultural and economic centre of central Europe consummate with genuinely opulent history. Founded during the Romanesque and flourishing by the Gothic, Renaissance and Baroque eras, Prague was the capital of the kingdom of Bohemia and the main residence of several Holy Roman Emperors, most eminently of Charles IV. It was a paramount city to the Habsburg Monarchy and its Austro-Hungarian Imperium.

Tracks and Sessions

Track 1 | Scaffolds in Tissue Engineering

Tissue engineering along with regenerative medicine can be used to create ‘Scaffolds’ in the human body which are used to support organs and organ systems that may have been damaged due to an injury or disease. Fundamentally, this process involves the in vitro construction of a patch (or a graft). This patch is made from a combination of stem cells and an artificial extracellular matrix (biomaterial). The engineered patch can then be surgically implanted into affected areas of the body that need reconstruction.

Scaffolds must be capable of performing the following functions:

Allow cell attachment and migration
Deliver and retain cells and biochemical factors
Enable diffusion of vital cell nutrients and expressed products
Exert certain mechanical and biological influences to modify the behaviour of the cell phase

Track 2 | Biomaterials

A biomaterial is any substance that has been engineered to interact with biological systems for a medical purpose - either a therapeutic or a diagnostic one. They are often used and/or adapted for a medical application, and thus comprises whole or part of a living structure or biomedical device which performs, augments, or replaces a natural function. Biomaterials are also used every day in dental applications, surgery, and drug delivery. A biomaterial may also be an autograft, allograft or xenograft used as a transplant material.

Track 3 | 3D Printing

3D printing is any of various processes in which a material is joined or solidified under computer control to create a three-dimensional object. 3D printing technologies are a promising and viable means of fabricating replicable and functional scaffolds capable of promoting tissue regeneration. Different 3D printing technologies have been developed to maximize the results. This operational procedure is still in its rudimentary stages and further experimentation is being performed before it can be used on an industrial level.

Track 4 | Plastic Surgery

The process of reconstructing, repairing and concerned with improving the function or appearance of parts of the body by the transfer of tissue, either in the treatment of injury or for cosmetic reasons is called plastic surgery.

Aesthetic surgery: Aesthetic surgery is an essential component of plastic surgery and includes facial and body aesthetic surgery.

Craniofacial surgery: Craniofacial surgery is divided into paediatric and adult craniofacial surgery.

Hand surgery: Hand surgery is concerned with acute injuries and chronic diseases of the hand and wrist, correction of congenital malformations of the upper extremities, and peripheral nerve problems.

Microsurgery: Microsurgery is generally concerned with the reconstruction of missing tissues by transferring a piece of tissue to the reconstruction site and reconnecting blood vessels.

Paediatric plastic surgery: Many birth defects or syndromes such as craniofacial anomalies, syndactyly, polydactyly, congenital hand deformities present at birth are best treated in childhood, and paediatric plastic surgeons specialize in treating these conditions in children.

Track 5 | Reconstructive surgery

Reconstructive plastic surgery is performed to correct functional impairments caused by burns; traumatic injuries, such as facial bone fractures and breaks; congenital abnormalities, such as cleft palates or cleft lips; developmental abnormalities; infection and disease; and cancer or tumours. It is usually performed to improve function, but it may be done to approximate a normal appearance. Plastic surgeons use microsurgery to transfer tissue for coverage of a defect when no local tissue is available. Free parts of skin, muscle, bone, fat, or a combination may be removed from the body, moved to another site on the body, and reconnected to a blood supply by suturing arteries and veins.

Track 6 | Flap Surgery

A flap is a section of living tissue that carries its own blood supply and is moved from one area of the body to another. Flap surgery can restore form and function to areas of the body that have lost skin, fat, muscle movement, and/or skeletal support. A local flap uses a piece of skin and underlying tissue that lie adjacent to the wound. A regional flap uses a section of tissue that is attached by a specific blood vessel. A musculocutaneous flap, also called a muscle and skin flap, is used when the area to be covered needs more bulk and a more robust blood supply. In a bone/soft tissue flap, bone, along with the overlying skin, is transferred to the wounded area, carrying its own blood supply. Further experimentation is going on in this field to analyse its potency in human beings.

Track 7 | Molecular Tissue Engineering

A comprehensive understanding of the involved ingredients of tissue engineering (cells, tissue inducing factors, genes, bio-materials) and the subtle relationships between them at molecular level can lead to a successful manipulation of reparative processes and a better biological substitute. Molecular tissue engineering, the offspring of tissue engineering and molecular biology, has gained an increasing importance in recent years. It offers the promise of not simply replacing tissue but improving their restoration to benefit mankind in the long run. Though still a new concept in the field of Molecular Biology, Molecular Tissue Engineering is a promising field for the near future.

Track 8 | Tissue Transplants

Tissue transplantation is a branch of tissue engineering which deals mainly with the transfer of a part of the skin to a deceased or wounded part of the body. It also forms the basis for complex transplantation procedures which involves transfer of an organ from a donor to a recipient. Organs that have been successfully transplanted include the heart, kidneys, liver, lungs, pancreas, intestine, and thymus. Tissues include bones, tendons (both referred to as musculoskeletal grafts), cornea, skin, heart valves, nerves and veins. Such practices are still facing problems and further research is being carried out to make this process cheaper and more available to the common people.

Track 9 | Ethics involving Tissue Transplant

Although Tissue (especially organ) transplantation is a boon to modern medicine, it raises a number of bioethical issues. One of the most common bioethical issue is organ trafficking. Some people illegally use this procedure to make huge amount of money by illegally procuring the organs from dead patients/people and selling them to dealers and hospitals. Again, in certain extreme cases informed consent does not take place and patients are killed to extract the organs or the families of the patients are not given their required payment. Transplantation tourism is also an emerging bio-ethical problem.

Track 10 | Diseases

Wounds can be inflicted on the body due to various mechanisms. When we fall on the ground, the skin gets scraped. Wounds can be inflicted due to fighting as well. The most common instances include accidents. When a wound is inflicted on our body, the surface of the skin is exposed to microorganisms as well as various environmental factors.

Track 11 | Cancer from wounds

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Wounds inflicted on the body due to various mechanisms can lead to cancer.

This includes:

Infection: Worldwide approximately 18% of cancer deaths are related to infectious diseases. Oncovirus include human papillomavirus, hepatitis B and hepatitis C viruses and human T-cell leukaemia virus-1. Bacterial infection may also increase the risk of cancer.

Physical agents: Some substances cause cancer primarily through their physical, rather than chemical, effects, such as those produced by kanger and kairo heaters (charcoal hand warmers), may produce skin cancer, especially if carcinogenic chemicals are also present. Frequent consumption of scalding hot tea may produce oesophageal cancer.

Track 12 | Radioactive contaminants

The main objective of researchers is to protect human health from unnecessary exposure to radiation. Current scientific understanding of the health effects of radiation exposure is used to create protective standards and guidance. Ionizing radiation has sufficient energy to cause chemical changes in cells and damage them. Some cells may die or become abnormal, either temporarily or permanently. By damaging the genetic material (DNA) contained in the body’s cells, radiation can cause cancer. Fortunately, our bodies are extremely efficient at repairing cell damage. The extent of the damage to the cells depends upon the amount and duration of the exposure, as well as the organs exposed. A very large amount of radiation exposure (acute exposure), can cause sickness or even death within hours or days.

Track 13 | Animal inflicted wounds

Wild and domestic animal bites are distinct from other injuries suffered by humans. Tearing, cutting, and crushing injuries may be combined with blunt trauma caused by falls. Animal bites may cause local infection, as bacteria residing in numerous environmental sources as well as inside the mouth of the animal contaminate the area of the injury. Domestic animal bites are common, and their incidence is rising. Wild animal attacks are often more spectacular and inflict a lot of damage on the human body.

Track 14 | Insect wounds and remedies

Insect bites and stings occur when an insect is agitated and seeks to defend itself through its natural defence mechanisms, or when an insect seeks to feed off the bitten person. Some insects inject formic acid, which can cause an immediate skin reaction often resulting in redness and swelling in the injured area. Stings from fire ants, bees, wasp hornets and other such insects are usually painful, and may stimulate a dangerous allergic reaction called anaphylaxis for at-risk patients. Bites from mosquitoes and fleas are more likely to cause itching than pain. Various types of creams, lotions and other products are being developed to combat these problems.

Track 15 | Traditional Medicine on Wound Healing

Wounds are the result of injuries to the skin that disrupt the other soft tissue. Healing of a wound is a complex and protracted process of tissue repair and remodelling in response to injury. Wound healing herbal extracts promote blood clotting, fight infection, and accelerate the healing of wounds. Phyto-constituents derived from plants need to be identified and screened for antimicrobial activity for management of wounds. Natural skin care uses topical creams and lotions made of ingredients available in nature such as herbs, roots, flowers, essential oils, etc.

Essential oils:

Essential oils are concentrated hydrophobic liquid containing volatile aroma compounds from plants. They play a major role in the healing of wounds in the human body. They are used in antiseptics and liniments in particular.

Wound healing by essential oils still has a long way to go before it hits the market globally.

Track 16 | Ulcers

An ulcer is a discontinuity or break in a bodily membrane that impedes the organ of which that membrane is a part from continuing its normal functions. The wounds from which ulcers arise can be caused by a wide variety of factors, but the main cause is impaired blood circulation.

Track 17 | Dermatology

Dermatology is the branch of medicine dealing with the skin, nails, hair and its diseases. It is a specialty with both medical and surgical aspects. Some very common problems include pimples and bumps on the skin, contagious skin diseases, colour problems on the skin, dry sweaty skin, itchy skin, rashes on the skin, hair and scalp problems, scaly skin, etc. Research focusses on all these problems to find out the best possible solution for the benefit of human life.

Track 18 | Skin wound care

Wound healing is a natural restorative response to tissue injury. Healing is the interaction of a complex cascade of cellular events that generates resurfacing, reconstitution, and restoration of the tensile strength of injured skin. Healing is a systematic process, traditionally explained in terms of 4 overlapping classic phases: haemostasis, inflammation, proliferation, and maturation.

Haemostasis: Haemostasis starts within the very first moments of the injury, where platelets play a role by aggregating, as well as by releasing cytokines, chemokines, and hormones.

Inflammatory Phase: In addition to activation of fibrin, thrombin activated by the coagulation cascades facilitates migration of inflammatory cells to the site of injury by increasing vascular permeability.

Proliferative Phase: Formation of granulation tissue is a central event during the proliferative phase. Its formation occurs 3-5 days following injury and overlaps with the preceding inflammatory phase.

Epithelialization: Epithelialization is the formation of epithelium over a denuded surface. It involves the migration of cells at the wound edges from one side of the incision to the other.

Track 19 | Embryonic Stem Cells

Embryonic stem cells (ES cells) are pluripotent stem cells derived from the inner cell mass of a blastocyst which is also known as the early-stage pre-implantation embryo. Embryonic stem cells of the inner cell mass are pluripotent, that is, they are able to differentiate to generate primitive ectoderm, which ultimately differentiates during gastrulation into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes embryonic stem cells from adult stem cells found in adults; while embryonic stem cells can generate all cell types in the body.

Track 20 | Adult Stem Cells

Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues. Production of adult stem cells does not destroy the embryo. They have the ability to divide or self-renew indefinitely and generate all the cell types of the organ from which they originate — potentially regenerating the entire organ from a few cells. Adult stem cells can be isolated from a tissue sample obtained from an adult.

Track 21 | Stem Cell Transplantation

A procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own that have been destroyed by disease or by the radiation or high doses of anticancer drugs that are given as part of the procedure. There are various ways of obtaining the stem cells. These stem cells may come from the blood or bone marrow of the patient, from a donor, or from the umbilical cord blood of a new-born baby. A stem cell transplant may be autologous (using a patient’s own stem cells that were collected and saved before treatment), allogeneic (using stem cells donated by someone who is not an identical twin), or syngeneic (using stem cells donated by an identical twin).

Track 22 | Genetic modification in Stem Cell Therapy

Gene therapy is a novel therapeutic branch of modern medicine. Gene therapy is still highly experimental but has the potential to become an important treatment regimen. In principle, it allows the transfer of genetic information into patient tissues and organs. Consequently, diseased genes can be eliminated, or their normal functions rescued. Furthermore, the procedure allows the addition of new functions to cells, such as the production of immune system mediator proteins that help to combat cancer and other diseases. The first successful clinical trials using gene therapy to treat a monogenic disorder involved a different type of SCID, caused by mutation of an X chromosome-linked lymphocyte growth factor receptor.

Track 23 | Nursing

Nursing is a profession within the health care sector focused on the care of individuals, families, and communities for them to attain, maintain, or recover optimal health and quality of life. Nurses may be differentiated from other health care providers by their approach to patient care, training, and scope of practice. Nurses practice in many specialties with differing levels of prescription authority. This is a widely studied branch when it comes to wound and health care.

Track 24 | Maternal and neonatal health

According to a survey, more than 4 million infants and five lakh women die each year worldwide during pregnancy as well as child birth related problems. Approximately two-thirds of infant deaths occur during the first month of life, making the first days of a child’s life critical to its survival and future health. The immediate causes of new-born death include infection, complications related to premature birth, birth asphyxia, and congenital anomalies. Poor maternal nutrition, maternal reproductive tract infections, low birth weight, and access to health services also contribute to new-born deaths. Many of these conditions can easily be prevented or treated. Research is still in its initial stages, but we hope for a promising future in the long run.

Track 25 | Patient Safety

Patient safety is the absence of preventable harm to a patient during the process of health care and reduction of risk of unnecessary harm associated with health care to an acceptable minimum. An acceptable minimum refers to the collective notions of given current knowledge, resources available and the context in which care was delivered weighed against the risk of non-treatment or other treatment. Every point in the process of care-giving contains a certain degree of inherent unsafely. Several countries have published studies showing that significant numbers of patients are harmed during health care, either resulting in permanent injury, increased length of stay in health care facilities, or even death. Clear policies, organizational leadership capacity, data to drive safety improvements, skilled health care professionals and effective involvement of patients in their care, are all needed to ensure sustainable and significant improvements in the safety of health care.

Track 26 | Toxicology

Toxicology is a discipline that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology. Medical toxicology, clinical toxicology and computational toxicology are important branches of this field and researchers involved in these fields are welcome to present their findings in the conference.

Track 27 | Safety of workers

It is a multidisciplinary field concerned with the safety, health, and welfare of people at work. Falls are one of the most common causes of fatal and non-fatal injuries among construction workers. Proper safety equipment such as harnesses and guardrails and procedures such as securing ladders and inspecting scaffolding can curtail the risk of occupational injuries in the construction industry.

The industries that follow these safety procedures include: Construction, Agriculture, Service Sector, Mining, Oil and gas extraction, Steel plants and others.

Track 28 | Nanotechnology

The chronic nature and associated complications of non-healing wounds have led to the emergence of nanotechnology-based therapies that aim at facilitating the healing process and ultimately repairing the injured tissue. A number of engineered nanotechnologies have been proposed demonstrating unique properties and multiple functions that address specific problems associated with wound repair mechanisms. This is still in its initial stages and scientists are doing their research on this field to make it affordable soon.

Track 29 | Microbiome on wound healing

There is increasing interest in the effects of bacteria on the processes of wound healing. All chronic wounds are colonized by bacteria, with low levels of bacteria being beneficial to the wound healing process. Chronic wounds support complex microbial communities comprised of a wide variety of bacterial phyla, genera and species, including some anaerobic bacteria not identified using culture-based methods. The progression from wound colonization to infection depends not only on the bacterial count or the species present, but also on the host immune response, the number of different species present, the virulence of the organisms and synergistic interactions between the different species.

Track 30 | Burns

Burns are caused when the cells present in the skin die during exposure to any hot object. The severity of the injury depends on the intensity of the heat and the length of time that it is in contact with either heat or certain chemicals. In addition to local injury at the site of burn, severe thermal injury over a large area of the skin, roughly 20 % total body surface area, results in acute systemic responses collectively known as burn shock. The initial inflammatory phase brings neutrophils and monocytes to the site of injury via localized vasodilation and fluid extravasation, thereby initiating an immune response that is later sustained by the recruitment of macrophages by chemokines. Mechanisms are being devised to combat this problem through tissue regeneration procedures and modern biotechnology.

Track 31 | Platelet Rich Plasma

Platelet rich plasma, commonly referred to as “PRP’, is a non-operative, permanent solution for conditions such as arthritis and ligament/tendon sprains and tears. Utilizing the body’s natural healing process, PRP therapy is a concentration of platelets that are injected into the damaged ligaments, tendons, and joints to promote tissue repair and accelerate healing. Creation of PRP is simple and painless. Though still a new concept in the field of Tissue Engineering, PRP technology is a promising field in the long run.

Track 32 | Fibrosis

Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This can be a reactive, benign, or pathological state. In response to injury, this is called scarring. Physiologically, fibrosis acts to deposit connective tissue, which can obliterate the architecture and function of the underlying organ or tissue. Defined by the pathological accumulation of extracellular matrix proteins, fibrosis results in scarring and thickening of the affected tissue 20^th century biotechnology.

Track 33 | Case studies

A case study is a research method involving an up-close, in-depth, and detailed examination of a subject of study (the case), as well as its related contextual conditions. Case studies can be produced by following a formal research method. Researchers performing case studies on wound care management as well as tissue engineering are welcome to deliver their findings at this conference.